Investment briefing

Every year, more than one million people face a cancer with no good answer.

BNCT Global is building the infrastructure that changes this. A network of treatment centers globally, anchored by a scientific standard developed over three decades. This document is for those who want to be part of it.

1,000,000+
Patients with no adequate option today
2020
Japan achieves full reimbursement
2024
Hospital accelerators available in Europe

The science

The science works.
Japan has been treating patients
for 50 years.

While Europe debated infrastructure, Japan treated patients. Since the 1970s, Japanese physicians have documented what BNCT can do for cancers that had no other viable option. The protocols are mature. The outcomes are repeated. The national health system has recognized it since 2020. This is not theory. It is 50 years of accumulated proof.

50+
Years of clinical use

Continuous treatment in Japan since the 1970s. The longest active BNCT programme in the world.

45%
Complete response

In recurrent head and neck cancers with no remaining treatment options. Conventional radiation therapy is less effective and has severe side effects.

Kankaanranta et al., IJROBP, 2012

53%
Overall survival at 2 years

Against 14% after stereotactic radiotherapy (Vargo et al., IJROBP 100, 2018).

Koivunoro et al., Radiother Oncol. 137, 2019

2020
Full reimbursement

Japan's national health system officially reimburses BNCT. Regulatory confirmation that the therapy works.

This is not a new idea.
It is a proven therapy waiting to reach Europe.

Europe is not waiting for proof. Europe is waiting for infrastructure. BNCT Global is building that infrastructure. The science was never the barrier.

Established in

Japan

Coming to

Europe

Prof. Dr. med. Wolfgang Sauerwein
Led by

Prof. Dr. med.
Wolfgang Sauerwein

Founder · BNCT Global GmbH · Essen

“We urgently need well-designed clinical trials. The window is open. The technology is ready. Now we act.”

  • Principal investigator, European EORTC BNCT trials
  • Specially Appointed Professor, Okayama University, Japan
  • Order of the Rising Sun, awarded by the Japanese Government
Why this is defensible
01
Blueprint advantage

Standardized center design eliminates the regulatory reinvention cost that blocked all previous European attempts.

02
Network effects

Each new center generates clinical data that accelerates reimbursement for all others. Solo centers cannot do this.

03
First mover in Europe

No network of BNCT centers exists today. The first to set the standard defines it for the continent.

04
50 years of Japanese proof

Prof. Sauerwein trained the researchers who built the Japanese system. The evidence exists. The infrastructure did not. Now it will.

The scale of the need

By 2040, cancer will be the leading cause of death globally.

The world is aging. Aging is the single greatest risk factor for cancer. The number of people who will need better treatment is not a projection. It is a demographic certainty.

BNCT is not a niche therapy. It is a platform for the cancers that conventional radiation cannot adequately treat. The addressable population grows every year without any change in the technology.

26M
New cancer cases per year today
Source: WHO Global Cancer Observatory 2022
35M+
Projected annual cases by 2050
A 77% increase driven almost entirely by aging populations
1M+
Patients per year who could benefit from BNCT today
Head and neck, glioblastoma, and other indications
The network

One reference center. Ten therapy centers. One standard.

Reference Center (location TBD)
Therapy Center
Blueprint connection

A global standard. Starting in Europe.

Network build-out roadmap

Phase 1 is what we are raising for. What follows is a separate conversation.

Phase 1 · NowEstablish the European network: 10 centers, one standard
This document

Reference center (location TBD). 10 affiliated therapy centers. Clinical trials for reimbursement approval. Blueprint model proven. The BNCT standard for Europe is written here. This is what we are building and what this investment case covers in full.

Phase 2 · 2030+
Expanded reach. Broader indications.

Available to qualified investors in the full briefing with Prof. Sauerwein.

Phase 3 · 2035+
The larger vision.

Shared exclusively in direct conversation.

Phase 1 stands entirely on its own as an investment case. What follows is not necessary to justify the decision. It is context for those who think in decades.

Next step

This is not a startup pitch.
It is an invitation to build something permanent.

Prof. Sauerwein presents the full case personally. No intermediaries. A 30-minute conversation with the person who built the scientific foundation this company stands on.

BNCT Global GmbH  ·  Essen, Germany  ·  Treat the Impossible