About BNCT Global

Three decades of work.
One window of opportunity.

Building BNCT into a clinical reality has been Prof. Sauerwein’s life’s work. The science was always there. The infrastructure is being built now.

Prof. Dr. med. Wolfgang Sauerwein
Award
Order of the Rising Sun
Japanese Government, 2019

A life dedicated to treating the impossible.

Prof. Dr. med. Wolfgang Sauerwein · Founder and President, BNCT Global GmbH

Prof. Dr. med. Wolfgang Sauerwein is Europe’s leading authority on Boron Neutron Capture Therapy. Based at the Universitätsklinikum Essen, he has spent more than three decades building the scientific, clinical, and regulatory foundations that BNCT Global now rests on.

He led the European Organisation for Research and Treatment of Cancer (EORTC) BNCT trials, the first and only systematic clinical BNCT programme in European history. He trained many of the researchers who went on to build Japan’s BNCT infrastructure, and holds a Specially Appointed Professorship at Okayama University in recognition of this work.

In 2019, the Japanese Government awarded him the Order of the Rising Sun for his extraordinary contributions to the field. He is President of the DGBNCT (German Society for Boron Neutron Capture Therapy) and co-editor of the definitive reference work on the subject, published by Springer.

BNCT Global is his answer to a simple question: the science has been proven in Japan for 50 years. Why does Europe still have no center? The answer has always been infrastructure, not evidence. BNCT Global builds the infrastructure.

Professor of Radiation Oncology, University Hospital Essen (retired)
Principal Investigator, European EORTC BNCT trials
Specially Appointed Professor, Okayama University, Japan
Recipient of the Japanese Order of the Rising Sun, Gold Rays with Neck Ribbon
President, DGBNCT (German Society for Boron Neutron Capture Therapy)
Co-editor, definitive BNCT reference work, Springer

Leadership

Running the company day to day.

Two managing directors lead operations, partnerships and growth, alongside founder Prof. Sauerwein.

André Minne

André Minne

Managing Director and Chief Financial Officer

André Minne is a German certified tax advisor and Diplom-Finanzwirt. After the tax administration he held senior positions in the tax departments of German DAX corporations, completed an international education in London and the German tax advisor examination, and held several managing director roles. Since 2002 he has worked as a partner in tax advisory firms, advising clients as a generalist on tax and related business matters.

Dr. Christian Köster

Dr. Christian Köster

Managing Director and Chief Legal Officer

Dr. Christian Köster has over thirty years of experience as in house and external legal counsel, working with lawyers across the world. A legal generalist with deep knowledge in IT and data protection law, international business law, mergers and acquisitions, joint ventures, compliance including antitrust and export control, and litigation. His industry experience spans manufacturing, chemicals, healthcare, retail and fashion, with projects across EMEA and roles at companies including Linde, PwC Legal and Gruner and Jahr. Languages: German and English.

Expertise

Seventeen leaders. One mission.

Our advisory board spans radiation oncology, medical physics, boron chemistry and cross-border industry, from Harvard and Nagasaki to the CNRS, Loma Linda and Varian.

Paul M. Busse

Joseph W. Cotchett Endowed Chair in Radiation Oncology, MGH, and Associate Professor, Harvard Medical School

Paul M. Busse

M.D., Ph.D., FASTRO. He completed his residency in Radiation Medicine at MGH, Harvard Medical School, and until 2003 was lead physician and Principal Investigator for the Harvard MIT BNCT Program. Chief of the Head and Neck Service and Clinical Director in the Department of Radiation Oncology at MGH, and a member of the NCCN Head and Neck Panel. Recognised as an ASTRO Fellow in 2018, an honor held by fewer than 3 percent of the membership.

Paul M. BusseJoseph W. Cotchett Endowed Chair in Radiation Oncology
Huan GiapChief Medical Officer
Evamarie Hey-HawkinsProfessor of Inorganic Chemistry (retired)
Georg LöerFounder
Thomas Rock MackieProfessor Emeritus of Medical Physics and Human Oncology
Patrick S. MartinAttorney at Law and Venture Capital Investor
Mitsuko MasutaniProfessor
Eiji MatsuuraProfessor Emeritus
Jean-Philippe PignolSenior Vice President
Lucie SanceyDirector of Research
Eduardo Daniel SantosDirector of Research Emeritus
Reinhard SchulteFull Professor of Radiation Medicine
Lembit SihverFounder and CTO
Rolf StähelinFounder and President
Birgit WortmannNuclear Engineer and invited expert
Florian HusenFounder and CEO
A history of BNCT

From discovery to clinical reality.
88 years in the making.

1932
Discovery

Gordon Locher first proposes the concept of neutron capture therapy for cancer treatment.

1951
First human trial

William Sweet and Gordon Brownell conduct the first BNCT treatments in humans at Massachusetts General Hospital.

1968
Japan begins

Hiroshi Hatanaka begins systematic BNCT treatment for brain tumors in Japan. The programme continues for decades.

1996
European EORTC trials

Prof. Sauerwein leads the first systematic European BNCT clinical programme under the EORTC framework.

2003
Petten facility

The European BNCT facility at Petten, Netherlands operates with Prof. Sauerwein as principal investigator.

2006
Europe pauses

Reactor-based neutron sources become unavailable in Europe. The technical barrier appears insurmountable.

2019
Accelerator breakthrough

Hospital-based particle accelerators reach clinical grade. The reactor barrier is gone. BNCT can move to any hospital.

2020
Japan reimbursement

Japan’s health system formally reimburses BNCT for head and neck cancer. BPA approved under the name Steboronine®.

2024
BNCT Global

Prof. Sauerwein founds BNCT Global GmbH. The European standard begins to be written.

Now
The window is open

The science is proven. The technology is ready. The infrastructure is being built. This is the moment.

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Advisory and partners

Built on the shoulders of decades of collaboration.

BNCT Global draws on a network of clinical, scientific, and regulatory expertise developed across Europe and Japan.

University Hospital Essen
EORTC (European Organisation for Research and Treatment of Cancer)
Okayama University, Japan
DGBNCT (German Society for Boron Neutron Capture Therapy)
RENOVATE, A Global Network